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containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA)
CD52
also known as cambridge pathology antigen 1 (CAMPATH-1)
is a 25-29 kD glycoprotein containing a large N-linked carbohydrate moiety
The actual molecule of CD52 is only 8-9 kD
It is expressed in the male reproductive tract and on virtually all lymphocytes (T and B cells)
as well as macrophages/monocytes
eosinophils
and red cells
CD52 is thought to play a role in carrying and orienting carbohydrates
CD52 is a potent target for complement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target for chronic lymphocytic leukemia (CLL)/lymphoma and immunosuppression
Reactivity: Human
